Cours : Genetics

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Genetics 10911206

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- An-Najah National University
  
  Faculty of Agriculture
  
  Department of Plant Production and Protection
  
  Course title: Genetics.
  
  Course number: 10911206.
  
  Instructor name: Dr. Heba Al-Fares.
  
  Compulsory / Elective: Compulsory
  
  Prerequisites : Botany and Zology
  
  __________________________________________
  
  Course Contents (description) :
  
  This course presents the principle and evidence leading to our understanding of gene concept and the role of DNA as genetic material. Patterns of inheritance, the relationship between genotype and phenotype, and the transmission, coding, and expression of genetic information are also included.
  
  Course Objectives :
  
  Introduce students to the principles of genetics and heredity of characters and the role of the DNA as genetic material.
  
  Intended Learning Outcomes and Competencies :
  
  At the end of this course students should be able to:
  
  1.      Recognize the basic role of the chromosome as carriers of the genetic material
  
  2.      Recognize the phase of cell cycle and cell division
  
  3.      Understand the structure of DNA and the mechanisms of replication, transcription, and translation.
  
  4.      Understand and explain the rules of Mendelian and non-Mendelian inheritance
  
  5.      Understand the inheritance of quantitative traits of importance in agriculture
  
  6.      Recognize the basic concepts of population genetics.
  
  This course is a prerequisite to plant breeding and animal breeding. In addition, it will help you to improve your skills in researching, group work, and presenting
  
  For full outline click here
- Forum
  
  News forum
- Forum
  
  What do you think you will learn in this course? Forum
- Chat
  
  Zoom link Chat
  
  Heba Alfares is inviting you to a scheduled Zoom meeting.
  
  Topic: Genetics
  Time: Apr 24, 2024 12:30 PM Jerusalem
  
  Join Zoom Meeting
  https://najah.zoom.us/j/93552147320?pwd=YVJ5Ym1ERkdXQUNWVVJmYlZiZVlBZz09
  
  Meeting ID: 935 5214 7320
  Passcode: 470562
  
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  Meeting ID: 935 5214 7320
  
  Find your local number: https://najah.zoom.us/u/abBHLDJJtS
- 20-12-2023
  https://najah.zoom.us/rec/share/SwfqZO6HnLf7fLUQ0Zs6cYuYGmKWcorwfvl1DyvJU3x79quaDNA7LrJLnByZabgf.t4QA6KVYts0pQhVE
  18-12-2023
  https://najah.zoom.us/rec/share/shhepdzx05lDXEb4SRudHpfTf2t9oHitX_d_xlqxw-yPBPB-v_jJSqKDBOGwgmfq.aXxIELU9AqsIbRSG
  13-12-2023
  https://najah.zoom.us/rec/share/IFCq9T9ZJRQMhcDT6AQW3M97B8HxfZer8cuSIyCYE9TraPNsvHzoo0TNvyv-pHUQ.71rlzWTAeOzhk4cr
  6/12/2023
  https://najah.zoom.us/rec/share/6jVWogvtGm-KW5jzFx4V6nSkqpXySoiHNc_UklwfK1ODO3YGt_MoOiVTdSV_pXK8.tJ4Dk2EoTN_9538x
  28/11/2023
  https://najah.zoom.us/rec/share/1d0DIl8r5PsBPHEM_Z2ldiQ5J6Zm2gS2KpOdTwDuSoRJ4G4dMUry4v2c1dyzCrVL.RoCgHMvg7C58G4hz
  27/11/2023
  https://najah.zoom.us/rec/share/8gzB4r8r5PO6DZeHL3QuIL6F2uI5v43fSDU5Z8NxOxlLglG2bCcmFGT4eXr7bMev.gdwAcyzSrPLrw3l0
  22/11/2023
  https://najah.zoom.us/rec/share/mCAZt7N35TcnEkR98wIixFymKEawYz436M9gEOdR3SuK67kCADppVH_1XaFpvv8u.ZFLGo-UJhvd_XgL5
  
  20/11/2023
  https://najah.zoom.us/rec/share/h2kwmipZhQ6yYRZMvRospatx1xPDR9YfNd9tpiY-4Imh_mFzuc_s0A5MAVluy_ET.nksJ8TPPxpsEq3bJ
  
  13/11/2023
  https://najah.zoom.us/rec/share/WmjoFDhl1n1z6EPHV-h8GWWa-B3ok17LYTQ8ZJTNVz9NLkwA3_zXPi6kSQESSa2x.8wlt96kPpB-USXGf?startTime=1699876825000
  8/11/2023
  https://najah.zoom.us/rec/share/dztPl9YZaJO70pHIS_pfuy231hfGmpMZSzLzNdhDvpug0mZQU1t5RR4B9kO29pje.M9R_Y8pLOvlauqqb?startTime=1699444731000
  6/11/2023
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  30/10/2023
  https://najah.zoom.us/rec/share/9lhKhxwUmjJKJ9XYaVVwxxZQPjdow7NxfBEEuvjhwO9xngtIj7EEEliALktiL1eU.titHTJNIOyMjoIgE?startTime=1698667083000
  25/10/2023
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  23/10/2023
  https://najah.zoom.us/rec/share/x2TVzH0Kbf821TMC_5SWhRO6fHrRtKtbBH8FpFEDTzup8-LVsVvQkhnCiQw3URQY.4k7uQvmaRlRNU-VH?startTime=1698058859000
  16/10-/2023
  https://najah.zoom.us/rec/share/dM4ldjdg5KW5L54BK8i0LSZ2MCXWU8IcHA3pPv-i_usf0oKQEL8xwpnJTEobIWs.8tvrZf6chey-F68U
  
  11/10/2023
  https://najah.zoom.us/rec/share/ezRGqckENr-pMIR6X6pxb7Uq7kSz2rMYlOvt3EYQ68Vnxe89gZhsjhGGNdKu5l7D.v-9-PQudFu0tLgEB?startTime=1697022925000
  9/10/2023
  https://najah.zoom.us/rec/share/TJEvG-sZcpSDmdmOEz2GPX8mgRzglkPozpspbir5Gd8VLV9FQe3wFCGlXtmi6yXD.vVflkihG4f0z6PM6
- Lectures 4-2024
  24-4-2024
  https://najah.zoom.us/rec/share/GMN9lf6EoJVMb2Q9of9269JDTFQ6vHVPjJP2V-sK0QQmzubKfHJZAeUPaMMQC1sB.4g3XV3QwEVUzC-aa
  27/4/2024
  https://najah.zoom.us/rec/share/z1WMn_TZ6D3ao1dTFTgKndsUFSo3Lqt0R_7I3tSTqqKR9x-Bn1MIqBhhM1yMbrQ3.sF6eoCBHqgiKiYbg
  4/5/2024
  https://najah.zoom.us/rec/share/0vX4NTZniHpo32HH17f5mSDAgqK99Slsj0xnOO8PmnmxzN2VMzec54VoGevbkNlJ.MGMqqtd0bHlsyx8K
  6/5/2024
  https://najah.zoom.us/rec/share/P1_NVt6StUF3n3X_0Kwl9HVKiz3-i6FSFlpu14WbSuwSWMspkWWST8C7GvPZYnT_.ERpLzHWsmh5ktA_V
  13/5/2024 late lecture 8 PM
  https://najah.zoom.us/rec/share/6Aay2rPaiWOZKDrh9ohxD34VxSwtmaI19RRTPK-zbs4eekozQcfvMTzBosp7nWpM.7Duz4zQQb9nF0jiH
  14/5/2024 late lecture 8 PM
  https://najah.zoom.us/rec/share/Fi9hfnYn3uU6OZ5PJnRkZlvQvwJBIx_2bKXmepDMTqJAFgsMiWMjfwAARMOPW7Fr.HNXG7M7WsMs98mmG
  15/5/2024 12:30
  https://najah.zoom.us/rec/share/s5J1X2bkqFfT4VBmKegigDHrF3YQ6meWqPEbBaRM3N6HuL05D4H_L1MyCtT8G0Pt.uj-0l_Z3zbpKmpAN
  18/5/2024 12:30 Saturday
  https://najah.zoom.us/rec/share/GUrnZTffyfAPNSNMmpx0aGXo2fbBb0Qkf3tSq_QRRQ676gnxfFy72s3cbD5vpCPc.6ZIRzgoeTPmKxell
  18/5/2024 2 PM
  https://najah.zoom.us/rec/share/qHSz9O4EQte7sn_Qq6n8ldXtYkKifI2P4s5fSMK-dHQc7XArci1w70ja4GmztJog.iEHTsXe2L-0DrkTb
  22/5/2024
  https://najah.zoom.us/rec/share/Wpil1Jdahb-ItW68raHWM0kSUoEyoj57uE43DJIXhtfZWmf4tSs2wt475DB0UVSc.Mxp4Mxxd9SDlfNLO
  25/5/2024
  https://najah.zoom.us/rec/share/8LHpBu8vM_w00hILbej7ZQgEYqMBm6zA2ycxwv13L_F9oBCsbigXqsavDSmM34s.V3w71cPKukZSU2go
18 August - 24 August
First Week : Cells and Chromosomes (Basic Cell Biology)
- Lectures Outline::
  
  Structure of Prokaryotic and Eukaryotic Cells
  
  Functions of cell organelles
  
  Classification of Chromosomes
  
  Chromosomal Aberration
  
  Haploids and Euploids
  
  Intended learning outcome:
  
  Describe the structure and function of the eukaryotic and prokaryotic cells
  
  Identify the function of cell organelles
  
  Differentiate between somatic and sex cells
  
  Describe the chromosome structure and function
  
  Explain the meaning of the terms homologous chromosomes, monoploid (haploid), diploid and polyploidy and their benefit in agriculture.
  
  Differentiate between normal and abnormal chromosome
  
  Recognize chromosome classification
  
  Distinguish among the different types of chromosome mutation including deletion, duplication, inversion, translocation and nondisjunction.
  
  Plan:
  
  First: Study the following PDF file about variation in chromosome structure and number .
- Fichier
  
  chapter 8 Fichier
- Second :Study the following PowerPoint file which about Cell Structure and chromosome structure
- Fichier
  
  Cell Structure and chromosome structure Fichier
- .
- Third:Find Comparison of Prokaryote, Animal and Plant Cells by Rodney F.Boyer. in the following animation
  
  Cell_struct ure
  
  Fourth : The following animation discribe the chromosomal structurabnormalities:
  
  Chromosomal Structur al
- Fifth View this video about chromosome abnormality and answer the following Assignment_1:
- Sixth : The following animation about chromosome_abnormalities
- Fichier
  
  chromosome_abnormalities Fichier
- Seventh :Join to the following forum
- Forum
  
  Cells and Chromosomes Forum
- Devoir
  
  Assignment 1 Devoir
- Fichier
  
  cell and chromosomes Fichier
25 August - 31 August
Second Week :The Cell Cycle and Cell Division
- Lecture Outline:
  
  Phases of the Cell Cycle
  
  Mitosis
  
  Meiosis
  
  Intended learning outcome :
  
  Describe the general structure, organization and division of cells, including the cell cycle, mitosis and meiosis.
  
  Identify and explain each of the processes involved in the cell cycle including cell growth, duplication of chromosome material, division of the nucleus (mitosis) and division of the cytoplasm (cytokinesis).
  
  Describe the process of mitosis with particular emphasis on the behaviour of the chromosomes.
  
  Describe the process of meiosis with particular emphasis on the behaviour of chromosomes during Meiosis I and Meiosis II.
  
  Explain the meaning of the terms chromatids, centromere, synapsis and tetrads.
  
  Differentiate between the process of mitosis and meiosis and explain the purpose for each.
  
  Explain the significance of meiosis for inheritance.
  
  Practical learning outcomes :
  
  prepare and view slides of root tip onion or other material showing mitosis
  
  investigate meiosis using prepared slides of plant tissues
  
  Plan:
  
  First:Study the following files about reproduction and chromosome transmission.
  
  .
- Fichier
  
  chapter 3 Fichier
- Fichier
  
  REPRODUCTION AND CHROMOSOME TRANSMISSION Fichier
- Second :The following animation describe Cell Cycle
- Fichier
  
  cell_cycle Fichier
- Third:The following animation about mitosis meiosis and cytokinesis.
- Fichier
  
  mitosis_meiosis Fichier
- Fichier
  
  MITOSIS AND CYTOKINESIS Fichier
- meiosis
- Fourth:Join to the following forum
- Forum
  
  Mitosis and meiosis Forum
- Fifth :After study the material do the following assignment
- Devoir
  
  Assignment 2 Devoir
- Fichier
  
  REPRODUCTION AND CHROMOSOME TRANSMISSION Fichier
- https://najah.zoom.us/rec/share/pyb_9C1mJAfK96zTxViZU8ai-wpgplSiepl42c0MvJPzrd14dDVsuCJBnT6Kg8w.Au_N3MagdegcFDei?startTime=1663747164000
1 September - 7 September
Third Week : DNA Structure and Replication
- Lecture outline
  
  Structure of DNA
  
  The Double Helix Model
  
  Nucleotides the Building Blocks of DNA
  
  DNA Replication:
  
  Replication in Bacteria
  
  Replication in Eukaryotes
  
  Intended learning outcomes:
  
  Explain the structure and function of DNA
  
  Describe in detail the organization and replication of DNA in the eukaryotic cell
  
  Rrecognize the structural elements of DNA at the molecular level: base pairs, sugar-phosphate backbone and double helix.
  
  Understand the base-pairing rules, and be able to recognise the purine and pyrimidine bases.
  
  Identify the nucleotide sequence of a given DNA section and replicate the sequence using a mini-model.
  
  Outline the semi-conservative replication of DNA
  
  Describe the contribution of Meselson and Stahl in revealing, from various hypotheses, which model correctly describes DNA replication
  
  Recognize the role of enzymes in each step of DNA replication
  
  Plan:
  
  First:Study the following file which contain :Identification of DNA as the Genetic Material ,Nucleic Acid Structure
  
  .
- Fichier
  
  Chapter 9 Fichier
- Fichier
  
  Structure of DNA Fichier
- Second :Study the following two files about DNA replication .
- Fichier
  
  DNA REPLICATION Fichier
- Fichier
  
  DNA Replication Fichier
- Fichier
  
  Chapter 11: DNA REPLICATION Fichier
- Third :Study the following file about the structure of DNA
- Fourth :View the following links and animations and answer the questions in the assignment 3
  
  1. DNA Structure
  
  2. Structural Basis of DNA Replication
  
  3.
  
  4.
  
  5.
- Devoir
  
  Assignment 3 Answer the following questions based on the linked animations above Devoir
- Fifth:Join the following forum
- Forum
  
  So roughly how long have we known about DNA? Pondered on its existence and confirmed? Forum
- Fichier
  
  DNA structure Fichier
- https://najah.zoom.us/rec/share/Szs3WEFq8sVCJhSSjjkBVtHSbFTDUSRMpfm0Iwy8iiPI04IGM7GYxxMisZ2PDI3A.UYCGe1eSuoRZlu8R
8 September - 14 September
Fourth week : Gene Transcription and RNA modification
- Lecture outline:
  
  DNA Transcription:
  
  The Central Dogma of Genetics
  
  Promoters, Transcription Factor, and RNA Polymerases
  
  Steps of Transcription
  
  Post-Transcriptional Modifications, of RNA
  
  Intended learning outcomes:
  
  Explain how-information flows from gene to protein
  
  Describe where transcription occur in prokaryotes and in eukaryotes
  
  Explain the process of transcription including the three major steps of initiation, elongation and termination.
  
  Describe the general role of RNA polymerase in transcription.
  
  Explain how RNA polymerase recognizes where transcription should begin.
  
  Distinguish among mRNA, tRNA and rRNA.
  
  Describe the process of transcription including initiation, elongation and termination and explain what enzymes, and transcription factors are needed for each stage.
  
  Plan:
  
  First :Study the following files about GENE transcription and RNA modification .
- Fichier
  
  Chapter 12: GENE TRANSCRIPTION AND RNA MODIFICATION Fichier
- Fichier
  
  GENE TRANSCRIPTION AND RNA MODIFICATION Fichier
- Fichier
  
  GENE TRANSCRIPTION AND RNA MODIFICATION Fichier
- Second :Study the following animation to understand transcription.
  
  Transcription
- Third :Based on the animation and files above answer the following questions
- Devoir
  
  Assignment 4 Devoir
- Fourth :Join the following forum
- Forum
  
  Junk DNA and transcription Forum
- https://najah.zoom.us/rec/share/4TNM-uVGmLG7nJpbvXLX9wej3wVfxkRHNB_ajuamDZ5Y3vl9ni8naLPdsDC8RCDq.8SqzLzV-79ky9H_4
15 September - 21 September
Fifth week:TRANSLATION OF mRNA
- Lecture outline:
  
  Overview
  
  Structure of tRNA and Ribosome's
  
  Steps of Translation
  
  Gene Structure and Function
  
  Intended learning outcomes
  
  Describe where translation occur in prokaryotes and in eukaryotes
  
  Explain the process of translation including the three major steps of initiation, elongation and termination
  
  Describe the process of translation including initiation, elongation and termination and explain what enzymes, and protein factors are needed for each stage.
  
  Explain how ribosome recognizes where translation should begin.
  
  Recognize the differences between translation in eukaryotic and prokaryotic
  
  Draw the structure of gene
  
  Recognize the function of gene body
  
  Describe the genetic code and discuss the extent to which it is true that the code is universal to all organisms
  
  Plan:
  
  First:Study the following two files about translation of mRNA.
- Fichier
  
  Chapter 12: TRANSLATION OF mRNA Fichier
- Fichier
  
  TRANSLATION OF mRNA Fichier
- Fichier
  
  Translation of mRNA Fichier
- Second :View the following links
  
  Translation Initiation
  
  https://highered.mcgraw-hill.com/sites/dl/free/0072835125/126997/animation24.html
  
  Translation Elongation
  
  https://highered.mcgraw-hill.com/sites/dl/free/0072835125/126997/animation25.html
  
  Translation Termination
  
  https://highered.mcgraw-hill.com/sites/dl/free/0072835125/126997/animation26.html
- Third :Based on the links above answer the following assignment and join the forum
- Devoir
  
  Assignment 5 Devoir
- Forum
  
  TRANSLATION OF mRNA Forum
- Devoir
  
  Assignment 6 Devoir
22 September - 28 September
Sixth Week: Mendelian genetics
- Lecture outline:
  
  In this Chapter we will first examine the outcome of Mendel’s crosses in pea plants.
  
  We begin our inquiry into genetics here because the inheritance patterns observed in peas are fundamentally related to inheritance patterns found in other eukaryotic species.
  
  In the second part of this chapter, we will become familiar with general concepts in probability and statistics. How are statistical methods useful?
  
  In addition, we will learn how to use statistics to test the validity of genetic hypotheses that attempt to explain the inheritance patterns of traits.
- Intended Learning Outcomes
  
  Demonstrate an understanding of the concept of heredity and a knowledge of the early ideas regarding the inheritance of traits.
  
  Describe the experiments of Gregor Mendel and explain how Mendel's work represents an example of the scientific process.
  
  Explain the principles of segregation, dominance, and independent assortment and indicate how Mendel's experiments support each.
  
  Describe the mathematical concept of probability and demonstrate its application to genetics problems.
  
  Demonstrate the transmission of genes in one-factor (monohybrid) and two-factor (dihybrid) crosses.
  
  Predict the genotypic and phenotypic ratios in one-factor (monohybrid) and two-factor (dihybrid) crosses.
  
  Explain the significance of a test cross.
  
  use and interpret the chi-squared test to test the significance of the difference between observed and expected results.
  
  Plan:
  
  First:Study the following file about MENDELIAN INHERITANCE.
- Fichier
  
  Mendelian genetics Fichier
- Fichier
  
  Chapter 2: MENDELIAN INHERITANCE Fichier
- Second:Go to the following link and study about Genes come in pairs.
  
  https://www.dnaftb.org/2/animation.html
  
  Third :Based on the above link and file answer the following assignment .
- Devoir
  
  Assignment 7 Devoir
- Fourth :Join the following forum to discuss Mendelian genetics
- Forum
  
  Mendelian genetics Forum
- Devoir
  
  Assignment 8 Devoir
- Fichier
  
  Mendelian Genetics Fichier
- https://najah.zoom.us/rec/share/w92TZk9_wWQtgf-jNfCyoVEkvJpdHPSoixNk1-lENtvbY-hzAlDOBrknuaRWYYbE.Xxt84pY2iTpbFrEj
- https://najah.zoom.us/rec/share/4wjr4K-1l_VaLaNoWrL9h3N08h74F__6GBchASEUNPIxUkjsq9mf9V087vevH805.hptpaRg-kgwuNRjA
29 September - 5 October
Seventh Week: Extensions of Mendelian inheritance.
- Lecture outline:
- Incomplete dominance
  
  Multiple Alleles and Codominance
  
  Overdominance
  
  Epistasis
  
  Incomplete Penetrance
  
  Intended Learning Outcomes
  
  Demonstrate the inheritance of traits governed by multiple alleles by predicting the genotypic and phenotypic ratios in crosses involving human blood types (ABO groups).
  
  Differentiate among dominance, incomplete dominance and co-dominance and illustrate the differentiation by describing one example for each.
  
  Use this knowledge of inheritance to track alleles through generations and categorize and predict genotypes and phenotypes
  
  Plan
  
  First:Study the following file a bout extensions of Mendelian inheritance .
- Fichier
  
  EXTENSIONS OF MENDELIAN Fichier
- Fichier
  
  Chapter 4: EXTENSIONS OF MENDELIAN INHERITANCE Fichier
- Second: Watch the following animation and answer the animated exercise to understand the concept of this chapter
  
  1. In this Activity you will examine variations on the simple Mendelian patterns incomplete dominance and codominance; multiple alleles; and gene interacations
  
  Extension of Mendelian inheritance
  
  2. In this Activity you will investigate the inheritance patterns resulting from a gene on the X chromosome that has no equivalent locus on the Y chromosome.
  
  X-Linked Inheritance
- Third :Join to the following fourm about Modification of Mendelian genetics
- Forum
  
  Modification of Mendelian genetics Forum
- Fichier
  
  Extensions of Mendelian inheritance Fichier
- Chat
  
  link to Facebook group ZOOM lecture at 9.30 Chat
  
  https://www.facebook.com/groups/660093491411786/?multi_permalinks=660094894744979&notif_id=1584306225153876&notif_t=feedback_reaction_generic
- https://najah.zoom.us/rec/share/4wjr4K-1l_VaLaNoWrL9h3N08h74F__6GBchASEUNPIxUkjsq9mf9V087vevH805.hptpaRg-kgwuNRjA
6 October - 12 October
Eighth Week : Linkage and Genetic Mapping in Eukaryotes:
- Lecture outline:
  
  In this chapter, we will consider the pattern of inheritance that occurs when different genes are situated on the same chromosome.
  
  In addition, we will briefly explore how the data from genetic crosses are used to construct a genetic map—a diagram that describes the order of genes along a chromosome.
  
  Intended Learning Outcomes
  
  Analyze data from a genetic cross and by observing the frequency of the offspring phenotypes be able to explain whether the genes are linked or unlinked
  
  Draw a genetic map indicating the map distance between the genes and then determining whether any interference is occurring between the genes.
  
  Explain the concepts of gene linkage and crossing-over.
  
  Plan:
  
  First:Study the following file about Genetic Linkage and Mapping in Eukaryotes
- Fichier
  
  Study Material: Genetic Linkage and Mapping in Eukaryotes Fichier
- Fichier
  
  Chapter 6 GENETIC LINKAGE AND MAPPING IN EUKARYOTES Fichier
- Third :Join to the following forum to discuss any topic about Linkage and Genetic Mapping in Eukaryotes
- Forum
  
  Linkage and Genetic Mapping in Eukaryotes Forum
- Fichier
  
  Linkage and Genetic Mapping in Eukaryotes Fichier
13 October - 19 October

Non disponible
20 October - 26 October
Tenth Week: POPULATION genetics
- Lecture outline:
  
  The genetic variation that occurs in populations
  
  The reasons why the genetic composition of populations may change over the course of several generations.
  
  Intended Learning Outcomes
  
  Use the Hardy-Weinberg equation to calculate expected number of carriers.
  
  Analyze populations for allele frequencies and genotype frequencies
  
  Discuss the assumptions of the Hardy-Weinberg Equilibrium for predicting population genotype frequencies from allele frequencies
  
  Plan:
  
  First :Study the following files about POPULATION genetics.
- Fichier
  
  Chapter 24: POPULATION GENETICS Fichier
- Fichier
  
  Study Material: POPULATION GENETICS Fichier
- Fichier
  
  population genetics Fichier
  
  It is the study of the properties of genes in populations
- Second:The following file contain solved problem about practical application on Hardy Weinberg
- Fichier
  
  Solved problems Fichier
- Third:Discuss POPULATION genetics in the following forum.
- Forum
  
  POPULATION GENETICS Forum
27 October - 2 November
Eleventh Week: QUANTITATIVE genetics
- Lecture outline :
  
  In this chapter, we examine how genes and the environment contribute to the phenotypic expression of complex or quantitative traits.
  
  We will begin with an examination of quantitative traits and how to analyze them using statistical techniques.
  
  We then look at the inheritance of polygenic traits and at quantitative trait loci—locations on chromosomes containing genes that affect the outcome of quantitative traits.
  
  Advances in genetic mapping strategies have enabled researchers to identify these genes.
  
  Last, we look at heritability and consider various ways of calculating and modifying the genetic variation that affects phenotype.
- Intended Learning Outcomes
  
  Understand the inheritance of quantitative traits of importance in agriculture
  
  Analyze genetic data
  
  Estimate heritability, and the component of genetic variance
  
  Plan:
  
  First: Study the following files about QUANTITATIVE genetics.
- Fichier
  
  Chapter 24: QUANTITATIVE GENETICS Fichier
- Fichier
  
  Study Material Fichier
- Second:Discuss the Inheritance of Quantitative Traits in the following forum.
- Forum
  
  Inheritance of Quantitative Traits Forum
- Devoir
  
  rDNA Devoir
- Fichier
  
  QUANTITATIVE genetics Fichier
3 November - 9 November
Twelfth week : RECOMBINANT DNA TECHNOLOGY
- Lecture outline :
  
  In this chapter, we will focus primarily on the use of recombinant DNA technology as a way to further our understanding of gene structure and function.
  
  We will look at the materials and molecular techniques used in gene cloning, and explore polymerase chain reaction (PCR), which can make many copies of DNA from a defined region.
  
  We will then explore techniques for identifying specific genes or gene products, as well as methods for detecting the binding of proteins to DNA or RNA sequences.
  
  Finally, we will examine how scientists analyze and alter DNA sequences through the techniques of DNA sequencing and site-directed mutagenesis (a procedure that allows researchers to make mutations within a cloned segment of DNA).
- Intended learning outcomes
  
  Recognize the types and function of restriction enzyme
  
  To understand the steps involved in using recombinant DNA technology to clone important protein.
  
  Understand the steps of PCR
  
  Explain Western blotting , Northern blotting and Southern blotting and their applications
  
  Plan:
  
  First :Study the following file
- Second :Watch the following interactive animation and answer the following assignment
- Fichier
  
  PCR animation Fichier
- Devoir
  
  Assignment 12 Devoir
- Third :The following link discuss the cycles of the polymerase chain reaction (PCR), 3D animation
  
  https://www.dnalc.org/view/15475-The-cycles-of-the-polymerase-chain-reaction-PCR-3D-animation-with-no-audio.html
  
  Fourth :Join to the following forum
- Forum
  
  Recombinant DNA Forum
- Fichier
  
  RECOMBINANT DNA TECHNOLOGY Fichier
- Devoir
  
  Criminal case Devoir
10 November - 16 November
Thirteenth week: Biotechnology .
- Lecture outline :
  
  In this chapter, we will examine how molecular techniques have expanded our knowledge of the genetic characteristics of commercially important species.
  
  We will also discuss examples in which recombinant microorganisms and transgenic animals and plants have been given characteristics that are useful in the treatment of disease or in agricultural production.
- Intended Learning Outcomes
  
  Describe the strategies and techniques used in cloning cDNA and genomic DNA and apply them to the expression of recombinant proteins in biotechnology and in the analysis of gene function.
  
  Discuss the impact of recombinant DNA technology in agriculture, forensic science, medicine, and pharmaceuticals.
  
  Plan:
  
  First:Study the following files about Biotechnology
- Fichier
  
  Chapter 19: Biotechnology Fichier
- Fichier
  
  Biotechnology Fichier
- Second :Join the following forum for any question
- Forum
  
  Biotechnology Forum
- Forum
  
  Questions for Student Discussion Forum
- Fichier
  
  lab1 Fichier
- Fichier
  
  lab2 Fichier
- https://najah.zoom.us/rec/share/A3hzV4VkalW7O_9RpTHx9mWgjF1aYoF9K261_aOTg19WEBNSlH9Bncur2YbY6FR8.3bKpqGoTgJxFjUQx
- New biotechnology
  
  https://najah.zoom.us/rec/share/A3hzV4VkalW7O_9RpTHx9mWgjF1aYoF9K261_aOTg19WEBNSlH9Bncur2YbY6FR8.3bKpqGoTgJxFjUQx
17 November - 23 November

Non disponible
24 November - 30 November

Non disponible
1 December - 7 December

Non disponible
8 December - 14 December

Non disponible
15 December - 21 December

Non disponible
22 December - 28 December
- Test
  
  Quiz 20 final Test
  
  تعليمات الامتحان
  
  1-الامتحان مكون من 20 سؤال لكل سؤال علامة واحدة ومجموع العلامات 20
  
  2- مدة الامتحان 35 دقيقة
  
  3- لا يمكن الرجوع الى نفس السؤال بعد الانتقال الى السؤال الذي يليه
  
  4- يجب فتح الامتحان من جهاز واحد فقط.
29 December - 4 January

Non disponible
5 January - 11 January
12 January - 18 January
- Test
  
  final exam Test
  
  الطلبة الأعزاء
  
  مدة الامتحان ساعة ونصف
  
  عدد الأسئلة ٩
  
  الكتابة على الموديل
  
  امنياتي لكم بالتوفيق

Aperçu des semaines

Genetics 10911206

An-Najah National University

Faculty of Agriculture

Department of Plant Production and Protection

Course title: Genetics.

Course number: 10911206.

Instructor name: Dr. Heba Al-Fares.

Compulsory / Elective: Compulsory

Prerequisites : Botany and Zology

__________________________________________

Course Contents (description) :

This course presents the principle and evidence leading to our understanding of gene concept and the role of DNA as genetic material. Patterns of inheritance, the relationship between genotype and phenotype, and the transmission, coding, and expression of genetic information are also included.

Course Objectives :

Introduce students to the principles of genetics and heredity of characters and the role of the DNA as genetic material.

Intended Learning Outcomes and Competencies :

1. Recognize the basic role of the chromosome as carriers of the genetic material

2. Recognize the phase of cell cycle and cell division

3. Understand the structure of DNA and the mechanisms of replication, transcription, and translation.

4. Understand and explain the rules of Mendelian and non-Mendelian inheritance

5. Understand the inheritance of quantitative traits of importance in agriculture

6. Recognize the basic concepts of population genetics.

18 August - 24 August

Structure of Prokaryotic and Eukaryotic Cells

Functions of cell organelles

Classification of Chromosomes

Chromosomal Aberration

Haploids and Euploids

Describe the structure and function of the eukaryotic and prokaryotic cells

Identify the function of cell organelles

Differentiate between somatic and sex cells

Describe the chromosome structure and function

Explain the meaning of the terms homologous chromosomes, monoploid (haploid), diploid and polyploidy and their benefit in agriculture.

Differentiate between normal and abnormal chromosome

Recognize chromosome classification

Distinguish among the different types of chromosome mutation including deletion, duplication, inversion, translocation and nondisjunction.

First: Study the following PDF file about variation in chromosome structure and number .

Second :Study the following PowerPoint file which about Cell Structure and chromosome structure

Third:Find Comparison of Prokaryote, Animal and Plant Cells by Rodney F.Boyer. in the following animation

Cell_struct ure

Fourth : The following animation discribe the chromosomal structurabnormalities:

Chromosomal Structural

Fifth View this video about chromosome abnormality and answer the following Assignment_1:

Sixth : The following animation about chromosome_abnormalities

Seventh :Join to the following forum

25 August - 31 August

Phases of the Cell Cycle

Mitosis

Meiosis

Describe the general structure, organization and division of cells, including the cell cycle, mitosis and meiosis.

Identify and explain each of the processes involved in the cell cycle including cell growth, duplication of chromosome material, division of the nucleus (mitosis) and division of the cytoplasm (cytokinesis).

Describe the process of mitosis with particular emphasis on the behaviour of the chromosomes.

Describe the process of meiosis with particular emphasis on the behaviour of chromosomes during Meiosis I and Meiosis II.

Explain the meaning of the terms chromatids, centromere, synapsis and tetrads.

Differentiate between the process of mitosis and meiosis and explain the purpose for each.

Explain the significance of meiosis for inheritance.

prepare and view slides of root tip onion or other material showing mitosis

investigate meiosis using prepared slides of plant tissues

First:Study the following files about reproduction and chromosome transmission.

Second :The following animation describe Cell Cycle

Third:The following animation about mitosis meiosis and cytokinesis.

Fourth:Join to the following forum

Fifth :After study the material do the following assignment

1 September - 7 September

The Double Helix Model

Nucleotides the Building Blocks of DNA

Replication in Bacteria

Replication in Eukaryotes

Explain the structure and function of DNA

Describe in detail the organization and replication of DNA in the eukaryotic cell

Rrecognize the structural elements of DNA at the molecular level: base pairs, sugar-phosphate backbone and double helix.

Understand the base-pairing rules, and be able to recognise the purine and pyrimidine bases.

Identify the nucleotide sequence of a given DNA section and replicate the sequence using a mini-model.

Outline the semi-conservative replication of DNA

Describe the contribution of Meselson and Stahl in revealing, from various hypotheses, which model correctly describes DNA replication

Recognize the role of enzymes in each step of DNA replication

First:Study the following file which contain :Identification of DNA as the Genetic Material ,Nucleic Acid Structure

Second :Study the following two files about DNA replication .

Third :Study the following file about the structure of DNA

Fourth :View the following links and animations and answer the questions in the assignment 3

Chromosomal Structur al

3.

4.