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ABC Type of ATPase

by منى امين سعد الدين صدر _ - Saturday, 12 March 2022, 7:22 AM
 
The ATP-binding cassette transporters (ABC transporters) are a transport system,ABC transporters often consist of multiple subunits, one or two of which are transmembrane proteins and one or two of which are membrane-associated AAA ATPases
transporters are also involved in multiple drug resistance, and this is how some of them were first identified. When the ABC transport proteins are overexpressed in cancer cells, they can export anticancer drugs and render tumors resistant

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